Reflux esophagitis in war-related sulfur mustard lung disease

Authors

  • Fateme Zali Imam Khomeini Hospital, Department of Internal Medicine, Division of Gastroenterology, Tehran University of Medical Sciences.
  • Hamidreza Abtahi Advanced Thoracic Research Center, Pulmonary and Critical Care Department, Imam Khomeini Hospital, Tehran University of Medical Sciences.
  • Mehrnaz Asadi Department of Internal Medicine, Imam Khomeini Hospital ,Tehran University of Medical Sciences, Tehran, Iran.
  • Nader Roushan Department of Internal Medicine, Division of Gastroenterology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
  • Najme Aletaha Department of Internal Medicine, Division of Gastroenterology, Tehran University of Medical Sciences, Tehran, Iran.
  • Reza Taslimi Department of Internal Medicine, Division of Gastroenterology, Tehran University of Medical Sciences, Tehran, Iran.
Abstract:

  Background: Sulfur mustard (SM) has acute and chronic effects on skin and mucosal surfaces. The aim of the study was to evaluate the frequency of esophagitis in a historical cohort of veterans who had been exposed to SM in Iran-Iraq war nearly 25 years ago.   Methods : One hundred two veterans with dyspepsia and/or heartburn underwent esophago-gastro-duodenoscopy. Of them, 52 cases had been exposed to SM and had chronic mustard lung disease. Controls included 50 veterans without SM exposure. Esophagitis was defined according to standard criteria.   Results : 81.6% of cases and 70.6% of controls had heart burn and/or regurgitation (p= 0.224). Esophagitis was seen in 40% of cases and 26.5% of controls (p= 0.155).   Conclusion : Based on our findings, SM exposure seems not to be associated with increased esophagitis.   

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Journal title

volume 28  issue 1

pages  188- 191

publication date 2014-01

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